Process for preparing 1,2,4-triazole-3-carboxamides

C - Chemistry – Metallurgy – 07 – D

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Details

260/313.3, 260/3

C07D 249/10 (2006.01) C07D 401/06 (2006.01) C07D 403/06 (2006.01)

Patent

CA 1223265

Abstract: There is disclosed a process for preparing a 1,2,4-triazole-3-carboxamide represented by the formula: Image wherein, R1 and R2 represent independently a hydrogen atom, an alkyl group, a cycloalkyl group or an aryl group, or both R1 and R2 represent an alkylene group linked with each other directly or through an oxygen atom or a nitrogen atom to form a ring together with the nitrogen atom to which they are attached, which comprises subjecting an oxamohydrazide represented by the formula: Image wherein R1 and R2 have the same meanings as defined above, to reaction with formamidine or a salt thereof.

452212

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