Angiogenesis inhibitor comprising fumagillin

Details Angiogenesis inhibitor comprising fumagillin Angiogenesis inhibitor comprising fumagillin

A - Human Necessities

61

K

167/199, 167/243

A61K 31/335 (2006.01) A61K 31/395 (2006.01) A61K 31/57 (2006.01) A61K 38/18 (2006.01) A61K 47/48 (2006.01) A61L 27/36 (2006.01) A61L 27/54 (2006.01) C07K 14/50 (2006.01) C08B 37/16 (2006.01)

Patent

CA 1333363

Fumagillin and its salts have an angiogenesis inhibiting activity and are useful for prophylaxis and treatment of diseases induced by abnormally stimulated neovascularization. The invention also provides certain pharmaceutical compositions comprising fumagillin or its salt, and an agent which potentiates angiogenesis inhibition such as heparin and sulfated cyclodextrins such as beta-cyclodextrin tetradecasulfate.

588398

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