Radiolabeled tumor imaging agent and method of preparation

Details Radiolabeled tumor imaging agent and method of preparation Radiolabeled tumor imaging agent and method of preparation

C - Chemistry, Metallurgy

07

D

167/47, 260/237.

C07D 487/22 (2006.01) A61K 51/04 (2006.01) C07F 5/00 (2006.01) G01N 33/60 (2006.01)

Patent

CA 1216288

ABSTRACT OF DISCLOSURE A novel chemical method of labeling porphyrin compounds, specifically hemato- porphyrin derivative(HPD), with the radionuclide Indium-111 or Indium-113m producing a radioactive tracer material suitable for biomedical applications. HPD labeled with Indium-lll or Indium-113m is biologically active in vivo and is preferentially taken up by tumors. This provides a simple and specific means of localizing and detecting neoplasms in man or in animal by scintigraphic imaging techniques.

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