C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
195/96, 260/1.39
C07D 495/04 (2006.01) A01N 43/90 (2006.01) A01N 63/02 (2006.01) C12P 17/18 (2006.01)
Patent
CA 1214130
ABSTRACT Several strains of X. nematophilus have been cultured aerobically and metabolites isolated from the supernatant culture fluid. The structure of five of these metabolites, to be known as xenorhabdins, were determined after spectroscopic and X-ray crystallographic data were correlated. The xenorhabdins are new compounds and exhibit antibacterial and pesticidal properties. Xenorhabdin concentrations approximating 50 mgL-1 have been achieved by batch and continuous fermentation processes. The invention encompasses the xenorhabdin compounds which have been characterised, as well as other compounds showing antibiotic and/or pesticidal properties isolated from xenorhabdin producing strains of Xenorhabdus, such as X.nematophilus and X.luminescens, processes for producing same, as well as formulations thereof and method of use.
439675
Akhurst Raymond J.
Gregson Richard P.
Lacey Michael J.
Lyons Graham R.
Rhodes Stuart H.
Biotechnology Australia Pty. Ltd.
Commonwealth Scientific And Industrial Research Organisation
Smart & Biggar
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