C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
150/3.2, 150/15.
C12Q 1/44 (2006.01) C12Q 1/36 (1985.01) C12Q 1/38 (1985.01)
Patent
CA 1254116
ABSTRACT OF THE DISCLOSURE An agent for the detection of esterolytic or proteolytic enzymes containing (a) an amino acid ester or peptide ester of a phenol, as the chromogenic enzyme substrate, and (b) a substance, which accelerates the enzymatic cleavage of the aminoacid ester or peptide ester bond of component (a), which is a polyaminoacid with molecular weight of between 1,000 and 2,000,000, preferably a polyaminoacid which is built up from aminoacids of the general formula Image in which R represents hydrogen or an optionally branched alkyl, cycloalkyl or aralkyl radical which has 1 to 15 C atoms, preferably 1 to 9 C atoms, and is optionally substituted by 1 or 2 hydroxyl, mercapto, carboxyl, amino or guanido groups.
476408
Miles Laboratories Inc.
Osler Hoskin & Harcourt Llp
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