Binder composition and analytical element having stabilized...

G - Physics – 01 – N

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G01N 33/558 (2006.01) G01N 33/52 (2006.01) G01N 33/543 (2006.01)

Patent

CA 1285872

BINDER COMPOSITION AND ANALYTICAL ELEMENT HAVING STABILIZED PEROXIDASE IN LAYER CONTAINING THE COMPOSITION Abstract of the Disclosure An analytical element has a peroxidase- labeled ligand analog distributed within a layer comprising from 0.1 to 10.0 y/m2 of poly(vinyl- alcohol) and from 0.2 to 20.0 g/m2 of glycerol. The concentration of the glycerol must be greater than 1 times the concentration of poly(vinyl- alcohol) in the layer. As a result, the peroxidase retains more of its stability prior to use. Such elements can be used to determine a number of different immunologically reactive analytes, such as digoxin.

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