Process for the preparation of permanent animal and human...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/00 (2006.01) C07K 14/00 (2006.01) C07K 14/52 (2006.01) C07K 16/00 (2006.01) C12N 5/02 (2006.01) C12P 1/00 (2006.01)

Patent

CA 1201396

ABSTRACT Process for obtaining permanently culturable animal and human cell lines and the use thereof. The present invention provides a process for obtaining permanently culturable animal and human cell lines by fusion of normal animal and human cells with biological components which bring about a cultur- ability in vitro, wherein normal animal or human cells are fused with cell fragments of transformed cells which alone are not capable of multiplication and then cultured in a culture medium without selection substances. The cell lines thus obtained can be used for obtaining cell products and for testing active substances.

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