Substituted n-piperidine-4-yl-n-pyrroloamines, a process for...

Details Substituted n-piperidine-4-yl-n-pyrroloamines, a process for... Substituted n-piperidine-4-yl-n-pyrroloamines, a process for...

C - Chemistry, Metallurgy

07

D

167/231, 260/277

C07D 401/12 (2006.01) A61K 31/445 (2006.01) C07D 409/14 (2006.01)

Patent

CA 1262547

ABSTRACT This invention relates to pyrrolylaminopiperidines and related compounds of the formula Image where R is hydrogen, loweralkyl, Arloweralkyl, cycloalkyl- loweralkyl, loweralkenyl and thienylloweralkyl; R1 is lower alkyl, hydrogen, loweralkylcarbonyl, loweralkoxycarbonyl, loweralkylthiocarbonyl of the formula Image alkyl, cyano, loweralkylaminocarbonyl, diloweralkylaminocarbonyl, cycloalkylcarbonyl, cycloalkylloweralkylcarbonyl and lower- alkenylcarbonyl; R2 is hydrogen, halogen and methyl; the pharmaceutically acceptable acid addition salts thereof, and to a process for their preparation. The compounds of the present invention have analgesic activity and can, therefore , be used as medicaments.

463494

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