2-pyrimidyl alkanesulfonates and methods for their...

C - Chemistry – Metallurgy – 07 – D

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C07D 239/34 (2006.01) C07D 239/36 (2006.01) C07D 239/42 (2006.01) C07D 295/15 (2006.01) C07D 401/12 (2006.01)

Patent

CA 1251796

-i- 2-PYRIMIDYL ALKANESULFONATES AND METHODS FOR THEIR PREPARATION AND USE Abstract Novel 2-pyrimidyl alkanesulfonates are prepared by reacting a 2-hydroxypyrimidine acid salt with an alkanesulfonyl chloride in the presence of an acid acceptor. The novel 2-pyrimidyl alkanesulfonates are advantageously employed to prepare 1-(cyanoalkyl)-4-(2-pyrimidyl)piperazines by reacting them with a novel 1-(cyanoalkyl)piperazine in the presence of an acid acceptor.

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