Pyridazinone derivatives

C - Chemistry – Metallurgy – 07 – D

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167/224, 260/264

C07D 237/04 (2006.01) A61K 31/50 (2006.01)

Patent

CA 1251448

A B S T R A C T Compounds of the formula (I) : Image (I) and pharmaceutically acceptable salts thereof are described, wherein R1 is hydrogen or methyl and R2 is C2-4alkyl. These compounds have inotropic, vasodilator, broncho- dilating and platelet aggregation inhibiting properties. Pharmaceutical compositions are described as are methods of use. Intermediates and processes for the preparation of the compounds of the formula (I) are described.

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