Preparation of n-substituted azetidine 3-carboxylic acid...

C - Chemistry – Metallurgy – 07 – D

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260/335.5

C07D 205/04 (2006.01)

Patent

CA 1241337

ABSTRACT PREPARATION OF N-SUBSTITUTED AZETIDINE 3-CARBOXYLIC ACID DERIVATIVES The novel ester, N-benzyl azetidine-3-carboxylic acid, methyl ester; and its use in the preparation of the corresponding free acid by a process which comprises reacting N-benzyl 3-cyano azetidine with methanol and hydrolysing the result methyl ester with hot water.

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