Treatment of tumors in mammals

Details Treatment of tumors in mammals Treatment of tumors in mammals

C - Chemistry, Metallurgy

07

H

167/202, 260/229

C07H 19/04 (2006.01) A61K 31/70 (2006.01) C07H 19/06 (2006.01) C07H 19/16 (2006.01)

Patent

CA 1264738

Abstract A series of difluoronucleosides have been found to be useful antineoplastic agents. In the compounds, the base portion may be, for example, a pyrimidine or purine base, and the sugar portion may be, for example, a difluoroxylose or difluororibose. The compounds are used to treat both solid and non- solid tumors, including, for example, leukemia, myeloma and lymphosarcoma.

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