Prostacyclin derivatives and their manufacture and use

Details Prostacyclin derivatives and their manufacture and use Prostacyclin derivatives and their manufacture and use

C - Chemistry, Metallurgy

07

D

260/235.01

C07D 307/935 (2006.01) C07D 307/937 (2006.01) C07F 7/18 (2006.01)

Patent

CA 1205467

ABSTRACT Novel prostacyclin derivatives of the general formula I Image (I) (in which B represepts C1-C10-alkylene, A represents -CH2-CH2-, trans-CH=CH- or -C?C-, W represents free or fuctionally modified -CHOH- or -C(CH3)OH-, D and E to- gether represent a direct bond or D represents optionally F and/or -OCH3 substituted bivalent aliphatic hydrocarbon containing up to 10 C and E represents O, S, -C?C- or a

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