A - Human Necessities – 61 – F
Patent
A - Human Necessities
61
F
3/121
A61F 2/06 (2006.01) A61L 27/16 (2006.01) A61L 27/34 (2006.01)
Patent
CA 1292597
ABSTRACT OF THE DISCLOSURE A tubular prosthesis having a composite structure comprising (i) tubular polytetrafluoroethylene having a microfibrous structure comprising small nodes interconnected with fibrils and (ii) materials which can be absorbed by a living body wherein (a) said polytetrafluoroethylene has a greater average fibril length on the outer surface than on the inner surface, and the fibrous structure of said polytetrafluoroethylene varies continuously across the thickness of the tube wall wherein said inner surface has said fibrous structure being predominantly oriented along the axial direction and said outer surface has said fibrous structure being predominantly oriented along the concentric direction; and (b) said materials which can be absorbed by a living body are collagen, at least one of albumin and chitosan, and heparin, and are distributed in such a manner that collagen is present in the portion of the tube wall which is closest to the outer surface thereof while at least one of albumin and chitosan is present in the portion of the tube wall which is closest to the inner surface thereof, and heparin is present in the inner surface of the tube wall.
525434
Asako Shigeru
Kashiwagi Tohru
Okabe Kazuhiro
Okita Koichi
Yamada Katsuya
Riches Mckenzie & Herbert Llp
Sumitomo Electric Industries Ltd.
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