Pteridine derivatives and method of treating cancer...

Details Pteridine derivatives and method of treating cancer... Pteridine derivatives and method of treating cancer...

C - Chemistry, Metallurgy

07

D

167/219, 260/242

C07D 475/00 (2006.01) C07D 475/04 (2006.01) C07D 475/08 (2006.01)

Patent

CA 1242440

ABSTRACT OF THE INVENTION 2,4-Diaminopteridine derivatives and the pharmaceutically acceptable salts thereof having potent anticancer activity are disclosed. Said derivatives possess the structural formula: Image wherein Y is NH2, OH or SH, R is Image Image Image and X is Image in which R' is H or CH3 or Image in which R and R' are as previously defined, provided, when Y is NH2, R' must be CH3 and when Y is OH, R' must be H.

473410

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