Diagnostic reagent and method

Details Diagnostic reagent and method Diagnostic reagent and method

C - Chemistry, Metallurgy

12

N

195/1.112

C12N 15/00 (2006.01) A61K 39/395 (2006.01) C07K 16/18 (2006.01) C07K 16/30 (2006.01) C12N 5/02 (2006.01) G01N 33/574 (2006.01)

Patent

CA 1201667

ABSTRACT There are provided monoclonal antibodies which react with human oncofetal ferritin and which do not react with human spleen ferritin or with liver ferritin; there are also pro- vided monoclonal antibodies which react both with human placenta oncofetal ferritin and with human adult spleen ferritin. There is provided a process for producing clones producing such antibodies and such clones, and an assay for the detection of human breast cancer based on the determination of oncofetal ferritin, which assay is based on such monoclonal antibodies.

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