Pharmaceutical composition containing cimetidine

Details Pharmaceutical composition containing cimetidine Pharmaceutical composition containing cimetidine

A - Human Necessities

61

K

167/237

A61K 31/415 (2006.01) A61K 9/00 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01)

Patent

CA 1304685

A PHARMACEUTICAL COMPOSITION CONTAINING CIMETIDINE ABSTRACT The invention provides a solid pharmaceutical dosage form comprising: (i) cimetidine: and (ii) antacid, wherein at least part of the antacid is in the form of granules comprising a freely water-soluble solid diluent, the antacid, and a rapidly swellable watar-insoluble disintegrant. Compositions of this type overcome the problem of the reduced bioavailability of cimetidine which can occur when cimetidine is co-administered with antacids.

566093

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