Insulin derivatives

Details Insulin derivatives Insulin derivatives

C - Chemistry, Metallurgy

12

P

195/128.2, 530/7

C12P 21/02 (2006.01) C07K 14/62 (2006.01)

Patent

CA 1339416

Exchanging asparagine in the A21 position of insulin into another amino acid gives novel insulin derivatives which are more stable and less immunogenic than the parent compound. The insulin derivatives can be prepared by transpeptidation of a biosynthetic precursor which may be expressed in a host organism such as a yeast.

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