4-hydroxy-benzhydrol derivatives, process for their...

Details 4-hydroxy-benzhydrol derivatives, process for their... 4-hydroxy-benzhydrol derivatives, process for their...

C - Chemistry, Metallurgy

07

C

260/618.8

C07C 39/12 (2006.01) C07C 37/055 (2006.01) C07C 37/20 (2006.01) C07C 39/367 (2006.01) C07C 43/23 (2006.01)

Patent

CA 1199939

Abstract The invention relates to new 4-hydroxy-benz- hydrols of the formula (I) Image (I) wherein R1 and R2 independently represent hydrogen, halogen, trihalomethyl, alkyl having from one to 4 carbon atoms or alkoxy having from one to 4 carbon atoms, with the proviso that if R1 is hydrogen, R2 is other than hydrogen or a 3-trifluoromethyl group, or if R1 is a 2-methyl group, R2 is other than a 5-methyl group. According to another aspect of the invention there are provided processes for the preparation of these compounds. The compounds of the formula (I) are pharma- cologically active. In particular, they are suitable for the treatment of acute ethanolic intoxication. Pharmaceutical compositions containing them as active ingredient are also within the scope of the invention.

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