Process for the preparation of tertiary carbinols containing...

Details Process for the preparation of tertiary carbinols containing... Process for the preparation of tertiary carbinols containing...

C - Chemistry, Metallurgy

07

D

260/292.2, 260/3

C07D 211/22 (2006.01)

Patent

CA 1340055

A process for the preparation of tertiary diphenyl carbinols containing a primary or secondary amine substituent on the aliphatic moiety attached to the carbinol function which consists in contacting a Grignard phenyl reagent with an amino-acid wherein the mobile protons are not masked in an aprotic inert organic solvent or a mixture thereof at a temperature between 20°C and the boiling temperature by the reaction mixture. The reaction products are useful as active ingredients of medicaments and intermediates for the manufacture thereof.

592387

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