Total synthesis of the utero-evacuant substance d,l- zoapatanol

Details Total synthesis of the utero-evacuant substance d,l- zoapatanol Total synthesis of the utero-evacuant substance d,l- zoapatanol

C - Chemistry, Metallurgy

07

D

260/355.5

C07D 313/04 (2006.01)

Patent

CA 1179358

ORTH 322 ABSTRACT TOTAL SYNTHESIS OF THE UTERO-EVACUANT SUBSTANCE D,L-ZOAPATANOL A method of synthesizing 2S*, 3R*-6E-(2- hydroxyethylidene)-2-methyl-2-(4,8-dimethyl-5-oxo- 7-nonenyl)-oxepan-3-ol, one of the active ingredients in the zoapatle plant, is described. The natural product is useful as a utero-evacuant agent.

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