Nalbuphine - narcotic analgesic composition and method of...

A - Human Necessities – 61 – K

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167/231

A61K 31/485 (2006.01)

Patent

CA 1200501

Title NALBUPHINE - NARCOTIC ANALGESIC COMPOSITION AND METHOD OF PRODUCING ANALGESIA Abstract of the Disclosure A narcotic analgesic composition particularly in oral dosage form is provided which provides excellent analgesia in a mammal while reducing or eliminating the respiratory depression and euphoria usually associated with narcotic analgesics. The composition comprises an analgesic effective amount of a narcotic analgesic or salt thereof and an analgesic effective amount of nalbuphine or a salt thereof. A method of producing analgesia in a mammal is also provided, this method comprises administering to a mammal parenterally or orally an analgesic effective amount of a narcotic analgesic or salt thereof and an analgesic effective amount of nalbuphine or a salt there- of. Administration of the narcotic analgesic and nalbu- phine can be either sequentially or simultaneously.

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