Substituted trans-1,2-diaminocyclohexyl amide compounds

Details Substituted trans-1,2-diaminocyclohexyl amide compounds Substituted trans-1,2-diaminocyclohexyl amide compounds

C - Chemistry, Metallurgy

07

D

167/207, 260/306

C07D 333/52 (2006.01) C07D 209/08 (2006.01) C07D 209/18 (2006.01) C07D 209/86 (2006.01) C07D 295/135 (2006.01) C07D 307/79 (2006.01) C07D 333/54 (2006.01) C07D 333/60 (2006.01) C07D 333/64 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01)

Patent

CA 1234808

ABSTRACT OF THE DISCLOSURE Substituted trans-1,2-diaminocyclohexyl amide compounds demonstrating selective opioid receptor binding possess utility as analgesic, diuretic, and psychotherapeutic agents. A method of preparing the compounds, pharmaceutical compositions employing the compounds, and a method of alleviating pain employing the compounds are also disclosed. The compounds have the general formula: Image (I) wherein n, A, R1, R2 and X are as defined in the disclosure and claims.

468526

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