Therapeutic uses of 2',5'-oligoadenylates

Details Therapeutic uses of 2',5'-oligoadenylates Therapeutic uses of 2',5'-oligoadenylates

A - Human Necessities

61

K

167/180, 167/202

A61K 31/70 (2006.01) C07H 21/00 (2006.01) C07H 23/00 (2006.01)

Patent

CA 1335356

Synthetic analogs of 2',5'-oligoadenylate (2-5A) wherein the aglycon, ribosyl moiety and/or terminal nucleoside have been modified are effective therapeutic agents, particularly against HIV infection. The analogs are utilized in compositions and methods for the treatment of disorders characterized by 2-5A pathway defects.

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