A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/164, 167/219
A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 9/50 (2006.01) A61K 31/505 (2006.01)
Patent
CA 1200496
ABSTRACT OF THE DISCLOSURE This invention relates to new preparations of dipyridamole or a physiologically acceptable acid addition salt thereof, for oral administration, with a relative bioavailability of over 100% (relative to dipyridamole solutions) and resulting in substantially lower blood level fluctuations, containing at least 5 equivalents of orally acceptable acidic excipient per mole of dipyridamole or an acid addition salt thereof, the dipyridamole or an acid addition salt thereof and acidic excipient preferably being present in intimate admixture. Other excipients may also be present, such as diffusion lacquers permeable to gastrointestinal fluid, swellable water-soluble polymers, water-insoluble polymers and water-repellent fats. Processes for preparing these preparations are also described.
405445
Bozler Gerhard
Brickl Rolf
Gruber Peter
Schepky Gottfried
Fetherstonhaugh & Co.
Thomae (dr. Karl) Gesellschaft Mit Beschrankter Haftung
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