C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/265.5
C07D 487/04 (2006.01) C07D 233/90 (2006.01) C07D 491/147 (2006.01)
Patent
CA 1216291
ABSTRACT OF THE INVENTION Provided are imidazoquinoxalines of the structures: Image and Image wherein R1, R5, R6 and R7 are independently H, alkyl, aryl, alkenyl, alkynyl, hydroxy, hydroxyalkyl, alkoxy, mercapto, mercaptoalkyl, alkylthio, amino, alkylamino, aminoalkyl, carboxaldehyde, carboxylic acid and salts thereof, carbalkoxy, alkanoyl, cyano, nitro, halo, triflurormethyl, sulfonyl, alkyl- sulfonyl, sulfonamido, or R1, R5, R6 and R7 may be taken together with the adjacent group to form a methylenedioxy group; ABSTRACT OF THE INVENTION (Page 2) R4 is H, alkyl, alkenyl, alkynyl, aryl, aralkyl, hydroxy,alkanoyl, or alkanoyloxy; R3 is H, cyano, tetrazolo, carboxaldehyde, hydroxy- alkyl, carboxylic acid and salts thereof or derivatives thereof such as esters or amides in which the substituent on the ester oxygen or amide nitrogen is alkyl, aryl, hydroxyalkyl, alkoxy- alkyl or amino alkyl; R2 and R8 are independently H, alkyl, aryl, halo, amino, alkylamino, arylamino, hydroxyamino, hydroxy, alkoxy, mercapto or alkylthio; and X is oxygen, sulfur, imino, hydroxyimino, and hydrazino. These new compounds have valuable pharmacological activity.
407473
Brown Richard E.
Lee Thomas D.
Mcfadden Fincham
Usv Pharmaceutical Corporation
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