2-(fluoroalkylthio)substituted penems, processes for...

C - Chemistry – Metallurgy – 07 – D

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260/111

C07D 499/00 (2006.01)

Patent

CA 1207754

A B S T R A C T Compounds are disclosed having the formula Image (1) in which the stereochemistry is 5R,6S,8R or 5R,6R,8S, A represents a fluoroalkyl group, straight chain or branched chain, with 1 to 3 fluorine atoms on the came carbon atom which is separated from the 2-S atom by at least one carbon atom, and R is hydrogen, a pharmaceutically acceptable cation or a metabolisable ester group. The compounds have antibacterial activity.

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