Pharmaceutical compositions containing more active ingredients

A - Human Necessities – 61 – K

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A61K 31/33 (2006.01) A61K 31/00 (2006.01) A61K 31/185 (2006.01) A61K 31/19 (2006.01) A61K 31/34 (2006.01) A61K 31/345 (2006.01) A61K 31/35 (2006.01) A61K 31/405 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) A61K 31/455 (2006.01) A61K 31/60 (2006.01) A61K 45/06 (2006.01) C07C 65/10 (2006.01) C07D 209/18 (2006.01) C07D 233/64 (2006.01)

Patent

CA 1211374

A b s t r a c t The invention relates to new anti-ulcer or anti-ulcer and antiinflammatory compositions, which contain a combination of an anti-ulcer agent or a salt thereof with salicylic acid or an alkali metal salt thereof and optionally a non-steroidal antiinflammatory agent or a salt thereof. As an anti-ulcer agent prefer- ably cimetidine or ranitidine is employed, while the preferred non-steroidal antiinflammatory agent is indomethacin. The new compositions according to the invention are devoid of the known side-effects observed as a result of concurrent administration of an anti-ulcer agent and a non-steroidal antiinflammatory agent, moreover they possess a synergistic anti-ulcer activity.

427820

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