Spergualin-related compounds and process for production thereof

Details Spergualin-related compounds and process for production thereof Spergualin-related compounds and process for production thereof

C - Chemistry, Metallurgy

07

D

260/314, 260/492

C07D 209/20 (2006.01) C07C 279/14 (2006.01) C07D 209/48 (2006.01) C07D 233/54 (2006.01)

Patent

CA 1199641

ABSTRACT OF THE DISCLOSURE This invention relates to novel spergualin-related compounds and to a process for the production thereof. The novel compounds, which have a high antitumor activity, are represented by the general formula Image (I) wherein R1 represents a hydrogen atom, hydroxyl group, or an alipllatic acyloxy group having 1 to 10 carbon atoms. R2 represents the residue of an .alpha.,.omega.-amino acid, other than a residue of .alpha.-hydroxyglycine, linked by acid amide groups to the adjacent carbonyl and amino groups, and m is 4, 5, or 6.

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