Substituted dipeptides, methods for their production,...

Details Substituted dipeptides, methods for their production,... Substituted dipeptides, methods for their production,...

C - Chemistry, Metallurgy

07

K

530/5

C07K 5/06 (2006.01) C07C 51/373 (2006.01) C07C 59/84 (2006.01) C07D 307/89 (2006.01) C07D 317/24 (2006.01) C07K 5/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1250091

A B S T R A C T Dipeptides are disclosed having the formula I Image I in which R1,R2,R3,R4,R5 and R6 are various substituents, p is 0,1 or 2 and the asterisks indicate chiral centres. The compounds inhibit the action of enkephalinase in mammals. Pharmaceutical compositions containing the above compounds are described.

441704

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