Immunologically active polypeptides with altered toxicity...

Details Immunologically active polypeptides with altered toxicity... Immunologically active polypeptides with altered toxicity...

C - Chemistry, Metallurgy

12

N

530/13, 167/135,

C12N 15/31 (2006.01) A61K 39/10 (2006.01) A61P 31/04 (2006.01) C07K 14/235 (2006.01) C12N 9/10 (2006.01) C12N 15/54 (2006.01)

Patent

CA 1341582

Immunologically active polypeptides with no or reduced toxicity useful for the preparation of an antipertussis vaccine. Method for the preparation of said polypeptides which comprises, cultivating a microorganism transformed with a hybrid plasmid including the gene/s which codes for at least one of said polypeptides in a suitable medium and recovering the desired polypeptide from the cells or from the culture medium.

581889

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