Monoclonal antibodies against tnf-–, hybridomas producing...

Details Monoclonal antibodies against tnf-–, hybridomas producing... Monoclonal antibodies against tnf-–, hybridomas producing...

C - Chemistry, Metallurgy

12

P

530/13, 167/139,

C12P 21/08 (2006.01) A61K 38/21 (2006.01) A61K 39/395 (2006.01) C07K 1/22 (2006.01) C07K 14/52 (2006.01) C07K 14/525 (2006.01) C07K 16/24 (2006.01) C12N 5/18 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01)

Patent

CA 1337518

A hybridoma cell line is disclosed which cell line expresses a monoclonal antibody which specifically recognizes and binds human TNF-.alpha., the hybridoma being formed by fusion of spleen cells from a mouse previously immunized with human TNF-.alpha. and murine myeloma cells. A monoclonal antibody which specifically recognizes and binds human TNF-.alpha. is also disclosed as well as a process for purification of TNF-.alpha..

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