Process for the preparation of .alpha.-hydroxycarboxylic...

C - Chemistry – Metallurgy – 07 – C

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260/389.1, 260/5

C07C 231/06 (2006.01) C07C 235/04 (2006.01) C07C 235/40 (2006.01)

Patent

CA 1307280

AE 3692 (8) 22772-1088 ABSTRACT The invention relates to a process for the preparation of .alpha.-hydroxycarboxylic acid amides of the formula: Image where R1 represents alkyl, alkaryl, aryl, alkenyl, heteroalkyl or heteroaryl, whether or not substituted, R2 represents hydrogen or methyl, or R1 and R2 together form cycloalkyl, by conversion of the corresponding cyanohydrins, and is characterized in that the conver- sion takes place in the presence of hydrogen peroxide and ammonia. By preference use is made of 2-6 moles hydrogen peroxide and 0.5-3 moles ammonia per mole cycanohydrin.

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