Synovial phospholipases

C - Chemistry – Metallurgy – 12 – N

Patent

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167/129, 167/139

C12N 15/55 (2006.01) A61K 39/39 (2006.01) A61K 39/395 (2006.01) C07K 16/40 (2006.01) C12N 9/18 (2006.01) C12N 9/20 (2006.01) C12Q 1/44 (2006.01) G01N 33/573 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1335800

Mammalian synovial phospholipase A2 (sPLA2) enzymes are provided, as well as DNA constructs encoding these enzymes, methods of producing the enzymes recombinantly, and antibodies thereto. Therapeutic methods employing anti-synovial phospholipase antibodies are also provided, in addition to diagnostic methods and other applications of sPLA2.

575732

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