Resilient transdermal drug-delivery device and compositions...

Details Resilient transdermal drug-delivery device and compositions... Resilient transdermal drug-delivery device and compositions...

A - Human Necessities

61

K

167/159

A61K 9/70 (2006.01) A61K 31/445 (2006.01) A61M 35/00 (2006.01)

Patent

CA 1309021

- 32 - RESILIENT TRANSDERMAL DRUG-DELIVERY DEVICE AND COMPOSITIONS AND DEVICES EMPLOYING FATTY ACID ESTERS/ETHERS OF ALKANEDIOLS AS PERCUTANEOUS ABSORPTION ENHANCERS Abstract A solid state, resilient laminated composite for administering estradiol transdermally consisting of a multiplicity of spaced structural laminas of a resilient elastomer, one of which forms the top of the composite, a viscoelastic hydrophobic polymer lamina containing propylene glycol monolaurate interposed between each structural lamina and a pressure-sensitive adhesive lamina that provides the basal surface of the composite and consists of a blend of a pressure-sensitive adhesive, estradiol, and propylene glycol monolaurate.

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