Cell lines

C - Chemistry – Metallurgy – 12 – N

Patent

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195/1.1

C12N 5/02 (2006.01) A61K 39/395 (2006.01) C07K 16/14 (2006.01) C12N 5/16 (2006.01)

Patent

CA 1173379

- 31 - ABSTRACT IMPROVEMENTS IN OR RELATING TO CELL LINES A rat myeloma cell line which does not express an immuno- globulin chain, YB2/3ØAg.20, is prepared from the cell line Y3-Ag 1.2.3 via a hybrid myeloma cell line. This cell line, and variants thereof prepared by passaging and/or cloning the line, may be fused with immunocyte cells from an animal sensitized to an immunogen to produce hybrid myeloma cell lines which provide a source of monoclonal antibodies to said immunogen.

381131

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