Carboxyalkyl amino acid derivatives of various substituted...

C - Chemistry – Metallurgy – 07 – K

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530/5.06

C07K 5/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1293589

Abstract CARBOXYALKYL AMINO ACID DERIVATIVES OF VARIOUS SUBSTITUTED PROLINES Carboxyalkyl dipeptides of the formula Image wherein R4 is a 3-, 4-, 5-, or 4,4-substituted proline are disclosed. These compounds are useful as hypotensive agents due to their angiotensin converting enzyme inhibition activity.

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