Composition and method for stabilization of dinucleotides

Details Composition and method for stabilization of dinucleotides Composition and method for stabilization of dinucleotides

C - Chemistry, Metallurgy

12

Q

150/3.3, 150/8.5

C12Q 1/25 (2006.01) C07H 19/207 (2006.01) C12N 9/96 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/52 (2006.01)

Patent

CA 1293678

Abstract A reduced dinucleotide, preferably nicotinamide adenine dinucleotide (NADH), is stabilized in an aqueous base liquid containing propylene glycol, boric acid and a buffer capable of buffering within a pH range of 8-11. The stabilized liquid contains greater than 50% (v/v) water. The remaining volume contains propylene glycol which has been chemically treated to remove oxidants. This reagent may be used by itself or in conjunction with an assay reagent system for use in the clinical laboratory.

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