Non-a, non-b hepatitis-associated antigen and diagnostic...

Details Non-a, non-b hepatitis-associated antigen and diagnostic... Non-a, non-b hepatitis-associated antigen and diagnostic...

A - Human Necessities

61

K

167/129, 167/44

A61K 39/29 (2006.01) G01N 33/576 (2006.01)

Patent

CA 1184846

A type non-A, non-B hepatitis-associated antigen is obtained by isolation and purification from non-A, non-B hepatitis autopsy liver and has the followingphysicochemical properties: molecular weight: 1,500,000 or more (gel filtration) sedimentation constant (10-13): 51,5S (ultracentrifugal analysis) buoyant density (g/cm3): 1.15 - 1.25 (in cesium chloride and in potassium bromide) particle diameter (nm): 26 - 37 electrophoretic mobility: .alpha.2 - .alpha.1 globulin region (in agarose gel). A type non-A, non-B hepatitis diagnostic reagent contains, as its principal ingredient, a conjugate of the above-described antigen.

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