Rnase l inhibitor as a marker for virus infections

Details Rnase l inhibitor as a marker for virus infections Rnase l inhibitor as a marker for virus infections

C - Chemistry, Metallurgy

12

Q

167/202, 150/9,

C12Q 1/70 (2006.01) A61K 31/70 (2006.01) C12Q 1/34 (2006.01)

Patent

CA 1337277

HIV-directed inhibitors of the natural 2'-5'A antiviral defense pathway, diagnostic procedures and materials, and modalities for treating viral disorders are described. HIV-induced inhibitors of RNase L in patients with lymphadenopathy (LAS), AIDS-related complex (ARC) and acquired immune deficiency syndrome (AIDS) were isolated and identified. Functional 2-5A is not able to activate RNase L in the peripheral blood mononuclear cells (PBMC) in these patients; endogenous dsRNA, especially mismatched dsRNA, activates 2-5A synthetase which results in an increased concentration by endogenous 2-5A.

560051

Affiliated with

Also associated with

Rating

Rnase l inhibitor as a marker for virus infections does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Rnase l inhibitor as a marker for virus infections, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Rnase l inhibitor as a marker for virus infections will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1286455