Thiazolyl derivatives useful as interediates for the...

C - Chemistry – Metallurgy – 07 – D

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260/302, 260/310

C07D 277/38 (2006.01) C07D 417/12 (2006.01)

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CA 1340499

Compounds of the formula: (see fig. I) wherein R2 is a lower alkyl having 4 to 8 carbon atoms, cycloalkyl, lower alkynyl having 2 to 6 carbon atoms, halo(lower)alkyl, carboxy(lower)alkyl or esterified carboxy(lower)alkyl, R6 is amino or protected amino, and R8 is hydrogen or lower alkyl, or the reactive derivatives at the carboxy group or salts thereof. These compounds are useful intermediates for the preparation of cephem or cepham compounds which can be employed for the treatment of infectious diseases caused by pathogenic microorganisms.

616635

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