Process for production of encainide

C - Chemistry – Metallurgy – 07 – D

Patent

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260/292.8

C07D 211/34 (2006.01) C07D 211/26 (2006.01) C07D 213/50 (2006.01)

Patent

CA 1213282

ABSTRACT OF THE DISCLOSURE An improved process for the preparation of 4-methoxy-2'[2-methyl-2 piperidyl)ethyl]benzanilide has been developed. This compound is also known as encainide. The process comprises essentially three steps starting with methyl anthranilate and 2-picoline and features a novel low-pressure hydrogenation sequence.

416079

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