Multilayer analytical element having an impermeable...

G - Physics – 01 – N

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150/15, 167/45

G01N 33/52 (2006.01) C12Q 1/00 (2006.01) G01N 33/542 (2006.01)

Patent

CA 1178536

ABSTRACT A multilayer analytical element for detecting a ligand in or the ligand binding capacity of a liquid sample of the type having a reagent layer incorpor- ating reagents which are responsive to the ligand in or the ligand binding capacity of the sample to give a detectable response, a radiation diffusing and block- ing layer, and a support layer, the improvement wherein the radiation diffusing and blocking layer is (a) interposed between the reagent layer and the support layer; (b) impermeable to the ligand, reagents Or the reagent layer, and products of their inter- reaction; and (c) inert to the ligand, reagents of the reagent layer, and products of their interreaction.

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