Chimeric rodent/human immunoglobulins specific for...

C - Chemistry – Metallurgy – 12 – N

Patent

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167/139, 167/47,

C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 51/10 (2006.01) C07K 16/30 (2006.01) C07K 16/46 (2006.01) C07K 19/00 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1340456

Chimeric rodent/human antibodies specific for cancer cell antigens are disclosed. The antibodies are made up of variable regions for cancer antigens derived from murine immunoglobulins and constant regions from human immunoglobulins. The murine variable regions retain antigen binding specificity when attached to human constant regions.

541501

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