Membrane plasmapheresis apparatus and process

A - Human Necessities – 61 – M

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182/15.2

A61M 1/03 (1980.01)

Patent

CA 1181697

MEMBRANE PLASMAPHERESIS APPARATUS AND PROCESS ABSTRACT OF THE DISCLOSURE A membrane plasmapheresis system introduces a flow of whole blood subject to a predetermined inlet pressure into a fluid path across a membrane which is suited for filtering the plasma from the whole blood and across which a predetermined pressure drop occurs. The plasma-poor blood is conducted from the membrane subject to a determinable plasma-poor blood pressure. Likewise, plasma filtrate is conducted from the membrane subject to a determinable plasma-filtrate pressure. The conduction of plasma filtrate is metered in response to the existent plasma-poor blood pressure to achieve and thereafter main- tain substantial equilibrium between the plasma poor blood pressure and the plasma filtrate pressure. A substantial- ly constant transmembrane pressure can thereby be main- tained at a level below which hemolysis occurs.

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