Process for preparing new 4h-1,2,4-triazole derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 249/08 (2006.01) C07C 243/38 (2006.01) C07D 317/46 (2006.01) C07D 405/04 (2006.01)

Patent

CA 1208226

PRECIS DE LA DIVULGATION: L'invention a pour objet un procédé pour préparer les composés (I): (I) Image où R1, R2, R3 et R4 sont hydrogène, hydroxy, alcoyle (1-4 carbo- nes) O-alc1 (1-4 carbones), NH2, NHalc2 (1-4 carbones), Nalc3alc'3 (1-4 carbones), halogène, CF3 ou NO2 ou R1 et R2 et/ou R3 et R4 forment un methylènedioxy, R est un hydrogène, alc4 (1-4 carbones), -CH2 CO2H, -CH2 CO2 alc5 (1-4 carbones) et leurs sels avec les acides. Les composés (I) possèdent de remarquables propriétés analgésiques.

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