Vaccines for prevention of gastroenteric disease

Details Vaccines for prevention of gastroenteric disease Vaccines for prevention of gastroenteric disease

C - Chemistry, Metallurgy

12

N

167/129, 195/1.3

C12N 15/00 (2006.01) A61K 39/02 (2006.01) C07K 14/245 (2006.01) C12N 15/68 (2006.01)

Patent

CA 1201076

VACCINES ABSTRACT A vaccine is described for prevention of gastro enteric disease caused in a mammalian species by a pathogenic microorganism. The vaccine comprises a nonpathogenic microorganism strain containing stable replicative plasmids, each having one or more genes non indigenous to the plasmid. The non-indigenous genes are either genes for an adhesin necessary for adherence of the pathogenic microorganism in the mammalian species or are genes for toxoids of toxins causative of the disease. Both types of genes may also be included in the same plasmid.

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