Quinolone and naphthyridine antibacterial agents containing...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 401/04 (2006.01) A61K 31/435 (2006.01) C07D 471/04 (2006.01)

Patent

CA 1339216

Novel quinolone and naphthyridine antibacterial agents are herein described having improved in vivo activity both orally and subcutaneously where the 7-side chain of such compounds contain an .alpha.-amino acid; also described are its corresponding optical isomers, methods of preparation as well as compositions and methods of treating infectious diseases. The naphthyridine antibacterial agents are of the following general structure: (see fig. I)

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