C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
150/15.1
C12Q 1/26 (2006.01) C12Q 1/54 (2006.01) C12Q 1/60 (2006.01) C12Q 1/62 (2006.01)
Patent
CA 1185883
ABSTRACT A novel enzyme of bilirubin oxidase and a conventional enzyme of laccase oxidize bilirubin to biliverdin without formation of hydrogen peroxide. Conjugated bilirubin in biological fluid may be quantitatively determined by reacting therewith the bilirubin oxidase of a microorganism of the genus Myrothecium origin, while total bilirubin in biological fluid may be quantitatively determined by reacting therewith the bilirubin oxidase or laccase under the presence of a specific additive compound.
414104
Akira Kosaka
Kenichi Hirano
Kuniyoshi Matsunaga
Noriaki Tanaka
Sawao Murao
Amano Pharmaceutical Company Limited
Gowling Lafleur Henderson Llp
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