Process for obtention of peripheral opiate antagonists

Details Process for obtention of peripheral opiate antagonists Process for obtention of peripheral opiate antagonists

C - Chemistry, Metallurgy

07

D

260/237.65

C07D 221/28 (2006.01)

Patent

CA 1220199

IN THE CANADIAN PATENT AND TRADEMARK OFFICE PATENT APPLICATION entitled : PROCESS FOR OBTENTION OF PERIPHERAL OPIATE ANTAGONISTS In the names of Alberto BIANCHETTI Dino NISATO Luciano MANARA Roberto SACILOTTO assignee : Societe anonyme styled : SANOFI 40, Avenue George V 75008 PARIS ABSTRACT OF THE DISCLOSURE Methyllevallorphanium salts having peripheral antagonistic activity of formula Image Yn(-) wherein Yn(-) represents the anion of a pharmaceutically acceptable acid other than halogen and n represents the number of negative charges of said anion are obtained by exchange of the halogen ion with the yn(-) anion.

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